| Title | Year | Genre |
|---|---|---|
| Sgrizam | 1986 | Action |
| Shackled | 1988 | Arcade |
| Shadow Dancer | 1991 | Action |
| Shadow of the Bear, The | 1985 | Adventure |
| Shadow of the Beast | 1990 | Action |
| Shadow Skimmer | 1987 | Action |
| Shadow Warriors | 1990 | Action |
| Shanghai | 1988 | Puzzle |
| Shanghai Karate | 1988 | Fighting |
| Shao Lin's Road Kung Fu | 1987 | Action |
| Shark | 1989 | Shooter |
| Sharkey's Moll | 1991 | Gun shooter |
| Sherman M4 | 1990 | Action |
| Shinobi | 1989 | Action |
| Ship of Doom | 1985 | Adventure |
| Ship Pilot | 1988 | Shooter |
| Shockway Rider | 1986 | Arcade |
| Shoe People, The | 1992 | Educational |
| Shogun | 1986 | Action |
| Short Circuit | ???? | Action |
| Shufflepuck Cafe | 1989 | Arcade |
| Side Arms | 1987 | Shooter |
| Sideral War | 1989 | Action |
| Sigma 7 | ???? | Shooter |
| Silent Service - The Submarine Simulation | 1986 | Action |
| Silent Shadow | 1988 | Shooter |
| Silkworm | 1988 | Shooter |
| Silva | 1985 | Adventure |
| Sim City | 1989 | Management |
| Simple 3D | ???? | Arcade |
| Simpsons, The - Bart vs The Space Mutants | 1991 | Platform |
| Simulador Profesional de Tenis | 1990 | Tennis |
| Sir Fred | 1986 | Arcade |
| Sir Lancelot | 1985 | Arcade |
| Sir Wood | 1989 | Action |
| Sito Pons 500cc | 1990 | Moto racing |
| Skaal | 1987 | Adventure |
| Skate Ball | 1989 | Sports |
| Skate Crazy | 1988 | Arcade |
| Skate or Die | 1989 | Skateboarding |
| Skate Rock | 1987 | Skateboarding |
| Skateboard Kidz | 1988 | Skateboarding |
| Skatin' USA | 1990 | Skateboarding |
| Skull and Crossbones | 1991 | Action |
| Skweek | 1989 | Arcade |
| Sky Hunter | 1988 | Action |
| Skyfox | 1985 | Aerial fighting |
| Skyx | 1988 | Arcade |
| Slaine | 1988 | Adventure |
| Slap Fight | 1987 | Shooter |
