| Title | Year | Genre |
|---|---|---|
| Sim Ant | ???? | Management |
| Sim City | ???? | Management |
| Sim Earth | ???? | Management |
| Sim Life | ???? | Strategy |
| SimCity Deluxe | ???? | Management |
| SimCity Terrain Editor | ???? | Management |
| Simon the Sorcerer | ???? | Adventure |
| Simulcra | ???? | Shooter |
| Simulman 01 - Simulman | ???? | Adventure |
| Simulman 02 - Nella Morsa di SS Dos | ???? | Adventure |
| Simulman 03 - Nel Regno di Doors | ???? | Adventure |
| Simulman 04 - Il Mondo Simulato | ???? | Adventure |
| Simulman 05 - I Rapitori di Sogni | ???? | Adventure |
| Simulman 06 - Luna Park | ???? | Adventure |
| Simulman 07 - Il Grande Freddo | ???? | Adventure |
| Simulman 08 - Il Giardino Virtuale | ???? | Adventure |
| Simulman 09 - Il Giocattolaio | ???? | Adventure |
| Simulman 10 - Pentagram | ???? | Adventure |
| Simulman 11 - Jailhouse Rock | ???? | Adventure |
| Sinbad | ???? | Adventure |
| Sink or Swim | ???? | Puzzle |
| Sir Fred The Legend | ???? | Action |
| Sixiang | ???? | Puzzle |
| Skaermtrolden Hugo | ???? | Arcade |
| Skarabeusz | ???? | Puzzle |
| Skarb Templariuszy | ???? | Adventure |
| Skarbnik | ???? | Adventure |
| Skat Deluxe | ???? | Cards |
| Skat Royal | ???? | Cards |
| Skate of the Art | ???? | Skateboarding |
| Skeleton Krew | ???? | Action |
| Ski or Die | ???? | Skiing |
| Skidmarks | ???? | Racing |
| Skidoo | ???? | Racing |
| Skidz | ???? | Sports |
| Skrull | ???? | Action |
| Skull & Crossbones | ???? | Action |
| Skweek | ???? | Arcade |
| Sky Cabbie | ???? | Arcade |
| Sky Chase | ???? | Action |
| Sky Fighter | ???? | Shooter |
| Sky High Stuntman | ???? | Shooter |
| Skyblaster | ???? | Action |
| Skyfox | ???? | Action |
| Skyfox II | ???? | Spaceship |
| Skyworker | ???? | Adventure |
| Slabs | ???? | Arcade |
| Slackskin & Flint | ???? | Arcade |
| Slam Raid | ???? | Shooter |
| Slam Tilt | ???? | Pinball |
